Toll-Like Receptor-4 and Lipoprotein Accumulation in Macrophages
نویسندگان
چکیده
منابع مشابه
Lipoprotein accumulation in macrophages via toll-like receptor-4-dependent fluid phase uptake.
Toll-like receptor (TLR)4 recognizes microbial pathogens, such as lipopolysaccharide, and mediates lipopolysaccharide-induced proinflammatory cytokine secretion, as well as microbial uptake by macrophages. In addition to exogenous pathogens, TLR4 recognizes modified self, such as minimally oxidized low-density lipoprotein (mmLDL). Here we report that mmLDL and its active components, cholesteryl...
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ژورنال
عنوان ژورنال: Trends in Cardiovascular Medicine
سال: 2009
ISSN: 1050-1738
DOI: 10.1016/j.tcm.2010.02.001